A recent NIH study indicates that depression is linked to osteoporosis in pre-menopausal women. The most significant loss of bone mass occurs in the hips, which are the main site of fractures in older adults. Hip fractures also cause the highest degree of loss of independence and institutionalization. The study did not related use of anti-depressants to bone loss but imbalances in immune-system substances as indicated by blood and urine samples. For women it’s a good idea to have a bone density test in the 40’s to establish a baseline and determine at an early age if there are issues before a fracture occurs. I had a bone density exam earlier this year and while I am still rated well, my score could have been better. I’m now taking calcium twice a day to make sure that my next reading either improves or at least remains the same.